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2024-5-19 6:53:40
Article

Staller E, Carrique L, Swann OC, Fan H, Keown JR,. Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun. 2024 May 15;15(1):4123.  Abstract  
submitted by kickingbird at 3 days ago from Nat Commun. 2024 May 15;15(1):4123 (via https://www.nature.com/articles/s41467-024-48470-3)
Avian influenza A viruses (IAVs) pose a public health threat, as they are capable of triggering pandemics by crossing species barriers. Replication of avian IAVs in mammalian cells is hindered by species-specific ...

Restori KH, Septer KM, Field CJ, Patel DR, VanInsb. Risk assessment of a highly pathogenic H5N1 influenza virus from mink. Nat Commun. 2024 May 15;15(1):4112.  Abstract  
submitted by kickingbird at 3 days ago from Nat Commun. 2024 May 15;15(1):4112 (via https://www.nature.com/articles/s41467-024-48475-y)
Outbreaks of highly pathogenic H5N1 clade 2.3.4.4b viruses in farmed mink and seals combined with isolated human infections suggest these viruses pose a pandemic threat. To assess this threat, using the ...

Meade PS, Bandawane P, Bushfield K, Hoxie I, Azcon. Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City. J Virol. 2024 May 15:e0062624.  Abstract  
submitted by kickingbird at 3 days ago from J Virol. 2024 May 15:e0062624 (via https://journals.asm.org/doi/10.1128/jvi.00626-24)
Highly pathogenic avian influenza viruses of the H5N1 clade 2.3.4.4b were detected in North America in the winter of 2021/2022. These viruses have spread across the Americas, causing morbidity and mortality ...

Ospina-Jimenez AF, Gomez AP, Osorio-Zambrano WF, A. Sequence-based epitope mapping of high pathogenicity avian influenza H5 clade 2.3.4.4b in Latin America. Front Vet Sci. 2024 Apr 29;11:1347509.  Abstract  
submitted by kickingbird at 3 days ago from Front Vet Sci. 2024 Apr 29;11:1347509 (via https://www.frontiersin.org/articles/10.3389/fvets.2024.1347)
High Pathogenicity Avian Influenza (HPAI) poses a significant threat to public and animal health. Clade 2.3.4.4b recently emerged from the Eastern hemisphere and disseminated globally, reaching the Latin ...

Jiang Y, Cai L, Jia S, Xie W, Wang X, Li J, Cui W,. Guanylate-binding protein 1 inhibits inflammatory factors produced by H5N1 virus through Its GTPase activity. Poult Sci. 2024 Apr 30;103(7):103800.  Abstract  
submitted by kickingbird at 3 days ago from Poult Sci. 2024 Apr 30;103(7):103800 (via https://www.sciencedirect.com/science/article/pii/S003257912)
The combination of inflammatory factors resulting from an influenza A virus infection is one of the main causes of death in host animals. Studies have shown that guinea pig guanosine monophosphate binding ...

Yu J, Wen Z, Hu W, Chen M, Zhang Y, Liu S, Wang G,. Influenza D Virus Infection in China, 2022-2023. Emerg Microbes Infect. 2024 May 13:2343907.  Abstract  
submitted by kickingbird at 5 days ago from Emerg Microbes Infect. 2024 May 13:2343907 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Influenza D virus (IDV) plays an important role in the bovine respiratory disease (BRD) complex. Its potential for the zoonotic transmission is of particular concern. In China, IDV has previously been ...

Thomazelli LM, Pinho JRR, Dorlass EG, Ometto T, Me. Evidence of reassortment of avian influenza A (H2) viruses in Brazilian shorebirds. PLoS One. 2024 May 13;19(5):e0300862.  Abstract  
submitted by kickingbird at 5 days ago from PLoS One. 2024 May 13;19(5):e0300862 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Influenza A viruses of the H2 subtype represent a zoonotic and pandemic threat to humans due to a lack of widespread specific immunity. Although A(H2) viruses that circulate in wild bird reservoirs are ...

Luczo JM, Spackman E. Epitopes in the HA and NA of H5 and H7 avian influenza viruses that are important for antigenic drift. FEMS Microbiol Rev. 2024 May 11:fuae014.  Abstract  
submitted by kickingbird at 6 days ago from FEMS Microbiol Rev. 2024 May 11:fuae014 (via https://academic.oup.com/femsre/advance-article/doi/10.1093/)
Avian influenza viruses evolve antigenically to evade host immunity. Two influenza A virus surface glycoproteins, the haemagglutinin and neuraminidase, are the major targets of host immunity and undergo ...

Evans TG, Castellino F, Kowalik Dobczyk M, Tucker. Assessment of CD8+ T-cell mediated immunity in an influenza A(H3N2) human challenge model in Belgium: a single centre, randomised, double-blind phase 2 study. Lancet Microbe. 2024 May 7:S2666-5247(24)00024-7.  Abstract  
submitted by kickingbird at 6 days ago from Lancet Microbe. 2024 May 7:S2666-5247(24)00024-7 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Background: Protection afforded by inactivated influenza vaccines can theoretically be improved by inducing T-cell responses to conserved internal influenza A antigens. We assessed whether, in an influenza ...

Wang Y, Li Q, Peng P, Zhang Q, Huang Y, Hu J, Hu Z. Dual N-linked glycosylation at residues 133 and 158 in the hemagglutinin are essential for the efficacy of H7N9 avian influenza virus like particle vaccine in chickens and mice. Vet Microbiol. 2024 May 9;294:110108.  Abstract  
submitted by kickingbird at 6 days ago from Vet Microbiol. 2024 May 9;294:110108 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H7N9 subtype avian influenza virus (AIV) poses a great challenge to poultry industry. Virus-like particle (VLP) is a prospective alternative for the traditional egg-based influenza vaccines. N-linked glycosylation ...

Liu H, Shaw-Saliba K, Westerbeck J, Jacobs D, Fens. Effect of human H3N2 influenza virus reassortment on influenza incidence and severity during the 2017-18 influenza season in the USA: a retrospective observational genomic analysis. Lancet Microbe. 2024 May 7:S2666-5247(24)00067-3.  Abstract  
submitted by kickingbird at 6 days ago from Lancet Microbe. 2024 May 7:S2666-5247(24)00067-3 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Background: During the 2017-18 influenza season in the USA, there was a high incidence of influenza illness and mortality. However, no apparent antigenic change was identified in the dominant H3N2 viruses, ...

Michael J Tisza, etc.,al. [preprint] Virome Sequencing Identifies H5N1 Avian Influenza in Wastewater from Nine Cities. https://doi.org/10.1101/2024.05.10.24307179.  Abstract  
submitted by kickingbird at 7 days ago from https://doi.org/10.1101/2024.05.10.24307179 (via https://www.medrxiv.org/content/10.1101/2024.05.10.24307179v)
Avian influenza (serotype H5N1) is a highly pathogenic virus that emerged in domestic waterfowl in 1996. Over the past decade, zoonotic transmission to mammals, including humans, has been reported. Although ...

Matthew Gonnerman, etc.,al. [preprint]A systematic review of laboratory investigations into the pathogenesis of avian influenza viruses in wild avifauna of North America. https://doi.org/10.1101/2024.05.06.592734.  Abstract  
submitted by kickingbird at 8 days ago from https://doi.org/10.1101/2024.05.06.592734 (via https://www.biorxiv.org/content/10.1101/2024.05.06.592734v1)
The lack of consolidated information regarding response of wild bird species to infection with avian influenza virus (AIV) is a challenge to both conservation managers and researchers alike, with related ...

Tabatha L. Cormier, etc.,al. [preprint]Seabird and sea duck mortalities were lower during the second breeding season in eastern Canada following the introduction of Highly Pathogenic Avian Influenza A H5Nx viruses. https://doi.org/10.1101/2024.05.03.591923.  Abstract  
submitted by kickingbird at 8 days ago from https://doi.org/10.1101/2024.05.03.591923 (via https://www.biorxiv.org/content/10.1101/2024.05.03.591923v1)
H5N1 clade 2.3.4.4b viruses have caused significant mortality events in various wild bird species across Europe, North America, South America, and Africa. In North America, the largest impacts on wild ...

Belen Aguero, etc.,al. [preprint]Novel introductions of human-origin H3N2 Influenza viruses in Swine, Chile. https://doi.org/10.1101/2024.05.08.593172.  Abstract  
submitted by kickingbird at 8 days ago from https://doi.org/10.1101/2024.05.08.593172 (via https://www.biorxiv.org/content/10.1101/2024.05.08.593172v1)
Influenza A virus (IAV) continuously threatens animal and public health globally, with swine serving as a crucial reservoir for viral reassortment and evolution. In Chile, H1N2 and H3N2 subtypes were introduced ...

René M Vigeveno and others. Long term evolution of human seasonal influenza virus A(H3N2) is associated with an increase in polymerase complex activity. Virus Evolution, veae030.  Abstract  
submitted by kickingbird at 8 days ago from Virus Evolution, veae030 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Since the influenza pandemic in 1968, influenza A(H3N2) viruses have become endemic. In this state, H3N2 viruses continuously evolve to overcome immune pressure as a result of prior infection or vaccination, ...

Hoy G, Stadlbauer D, Balmaseda A, Kuan G, López R,. Humoral correlates of protection against influenza A H3N2 virus infection. J Infect Dis. 2024 May 9:jiae258.  Abstract  
submitted by kickingbird at 8 days ago from J Infect Dis. 2024 May 9:jiae258 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Influenza virus remains a threat to human health, but gaps remain in our knowledge of the humoral correlates of protection against influenza virus A/H3N2, limiting our ability to generate effective, ...

Wang Y, Li X, Lv X, Li Y, An Q, Xiu Y, Lv X, Song. H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China. Virus Genes. 2024 May 9.  Abstract  
submitted by kickingbird at 8 days ago from Virus Genes. 2024 May 9 (via https://link.springer.com/article/10.1007/s11262-024-02068-5)
H6 avian influenza virus is widely prevalent in wild birds and poultry and has caused human infection in 2013 in Taiwan, China. During our active influenza surveillance program in wild waterfowl at Poyang ...

Cheng P, Zhai K, Han W, Zeng J, Qiu Z, Chen Y, Tan. Characterizing the antigenic evolution of pandemic influenza A (H1N1) pdm09 from 2009 to 2023. J Med Virol. 2024 May;96(5):e29657.  Abstract  
submitted by kickingbird at 8 days ago from J Med Virol. 2024 May;96(5):e29657 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29657)
The H1N1pdm09 virus has been a persistent threat to public health since the 2009 pandemic. Particularly, since the relaxation of COVID-19 pandemic mitigation measures, the influenza virus and SARS-CoV-2 ...

S. Lair et al. Outbreak of Highly Pathogenic Avian Influenza A(H5N1) Virus in Seals, St. Lawrence Estuary, Quebec, Canada. Emerg Infect Dis. 2024 Jun.  Abstract  
submitted by kickingbird at 10 days ago from Emerg Infect Dis. 2024 Jun (via https://wwwnc.cdc.gov/eid/article/30/6/23-1033_article)
We describe an unusual mortality event caused by a highly pathogenic avian influenza (HPAI) A(H5N1) virus clade 2.3.4.4b involving harbor (Phoca vitulina) and gray (Halichoerus grypus) seals in the St. ...

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